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1/6/2019

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Let's Review that final


 ​
​1. What is a biomolecule?  They are also called the four major classes of organic
    compounds. 
​​​
    
    
A biomolecule or biological molecule is one of Life's building blocks. 
   
​    Examples are: proteins, carbohydrates, lipids, and nucleic acids

    
Carbohydrates: short term energy storage: sugars, starch, and cellulose. 
                                 CHO (Carbon, Hydrogen, Oxygen)


    Lipids: fats, make cell membrane lipid bilayer, long term energy storage. 
                 CHO (Carbon, Hydrogen, Oxygen)

    Proteins: chains of 
amino acids, Provide: structure, movement, muscle, hair, collagen,
                     enzymes, antibodies.  
                     CHONS (Carbon, Hydrogen, Oxygen, Nitrogen, Sulfur)

  
    Nucleic Acids: store and transmit genetic information: DNA, RNA
                              DNA is a double helix
                              RNA is a singe strand
                              CHNOP (Carbon, Hydrogen, Nitrogen, Oxygen, Phosphorous)

    All nucleic acids are made up of the same building blocks (monomers),

    the monomers are called "nucleotides." 


    Nucleotide: a compound consisting of a nucleoside linked to a phosphate group. 
    Nucleotides form the basic structural unit of nucleic acids such as DNA.


    The five monomers or nucleotides are: uracil, cytosine, thymine, adenine, and guanine

    Nucleotides in DNA contain four different nitrogenous bases: 
    Thymine, Cytosine, Adenine, or Guanine.

   RNA contains uracil, instead of thymine

   6 elements needed for life: Carbon, Hydrogen, Oxygen, Nitrogen, Phosphorous, Sulfur
​


​2. Why do they (biomolecules) matter?

    Biomolecules are essential for life, they are  
essential to some biological process such
    as cell division, nutrient transport, or development.

    Examples:

    
Carbohydrates: 
                Sugars in fruit, starch in roots (potatoes, yams), and cellulose in plants (celery) 
    Lipids:   
                Seed oils, plant oils, waxes ( the waxy cuticle that keeps plants from dehydrating)
    Proteins:
                Chitin: the protein that makes insect exoskeleton, crustacean shells, and                                              mushrooms
                Keratin: the protein in skin hair, nails
                Enzymes: 
Amylase: found in saliva, breaks down starch molecules into
                                                   smaller 
glucose and maltose molecules
    Nucleic Acids:  DNA, RNA, instructions of how to make biomolecules that the
                                living being needs to do their work
​

 
​​3. What is the difference between an atom and a molecule?
  • An atom a fundamental piece of matter, the items on the periodic table of elements
  • An atom itself is made up of three tiny kinds of particles called subatomic particles: protons, neutrons, and electrons. 

    The protons and the neutrons make up the center of the atom called the nucleus
​    and the electrons fly around above the nucleus in a small cloud.

    A molecule is a group of atoms bonded together, representing the smallest
    fundamental unit of a chemical compound

   
    Extra information:
​
    Types of bonds: 
​                                 A covalent bond, also called a molecular bond, is a chemical bond that
                                 involves the sharing of electron pairs between atoms.


                                 Ionic bonding is the complete transfer of valence electron(s) between 
                                 atoms and is a type of chemical 
bond that
                                 generates two oppositely charged 
ions. Usually found in Metals.

                                 A 
polar bond is a covalent bond between two atoms where the 
                                 electrons forming the 
bond are unequally distributed.
                                 This causes the molecule to have a slight electrical dipole moment
                                 where one end is slightly positive and the other is slightly negative.

​
Carbon is ideal for sharing electrons - forming covalent bonds


​4. How does an enzyme help with digestion and metabolism?

     Enzymes speed up chemical reactions and speed up metabolism. 
     The effectiveness of an enzyme can be affected by temperature, pH, concentration
     of enzyme, and concentration of substrate 

    Types of Enzymes:
  • Proteases and peptidases split proteins into small peptides and amino acids.
  • Lipases split fat into three fatty acids and a glycerol molecule.
  • Amylases split carbohydrates such as starch and sugars into simple sugars such as glucose.
  • Nucleases split nucleic acids into nucleotides.

If a word ends with -ase, it is probably an enzyme
​


​5. Does an enzyme need to fit into a specific space or “doorway” to work?

     Our review calls it the lock and key model.
​
    Enzymes are specific. Only molecules with the correct shape can fit into the
    
enzyme. Just like only one key can open a lock, only one type of enzyme can speed
    up a specific reaction. This is called the 
lock and key model.

Picture


​6. How do we maintain homeostasis?

    Homeostasis is 
the tendency toward a relatively stable equilibrium between     
    interdependent elements, especially as maintained by physiological processes.

    F
ive body functions that monitor homeostasis are: temperature, glucose, blood
    pressure, toxins, and pH.


    Examples from class:
  • Storing lipids for blubber
  • cold blooded animals going out to get sun
  • Penguins reducing the blood flow to their feet to keep their core warm
  • Seals reducing oxygen flow to outer limbs and focusing on oxygenating brain and heart so they can dive longer
  • Plants absorbing sunlight for photosynthesis and adapting their color to maximize photosynthesis 
  • Plants closing stomata during the day to prevent loss of moisture 

    Examples in humans:
  • Body pH: The kidneys excrete excess acids and bases to regulate pH in blood.
  • The lungs control pH levels by excreting carbon dioxide. When a person exhales, the diaphragm pushes carbon dioxide out of the body. The pH of the blood changes when the depth and speed of breathing change, making it possible to adjust blood pH in less than a minute.
  • Body Temperature: ​Normal body temperature is 37 degrees C or 98.6 degrees F. 
  • The body controls temperature by producing heat or releasing excess heat, through sweat or focusing blood flow in mid body.
  • Calcium Levels: The bones and teeth contain approximately 99 percent of the calcium in the body, while the other 1 percent circulates in the blood.
  • ​ If blood calcium levels decrease too much, the parathyroid glands activate their calcium-sensing receptors and release parathyroid hormone (PTH).
  • PTH signals the bones to release calcium to increase the amount of calcium in the bloodstream. If calcium levels increase too much, the thyroid gland releases calcitonin and fixes more calcium in the bones. 
  • Fluid Retention: Hormones help to regulate this balance by causing the excretion or retention of fluid. If the body does not have enough fluid, antidiuretic hormone signals the kidneys to retain fluid and decrease urine output. If the body has too much fluid, it suppresses aldosterone and signals the excretion of more urine.
​


​7. What is osmosis?

     
     a. How water moves into a cell

     b. A protein
     c. 
A type of DNA strand
     d. The body’s ability to produce sweat
​
Osmosis is the spontaneous net movement of water across a semipermeable membrane from a region of low solute concentration to a more concentrated solution, up a concentration gradient.

Osmotic Balance: Osmoregulation controls this balance of water/salt concentrations.

Salts go from high concentration to low concentration, salt wants to get in the water 

Water moves from low solute to high solute, water wants to dilute the salt



​8. What does the figure below represent?
Picture
      a. DNA
      b. RNA
      c. Protein
      d. Amino Acid
​
Deoxyribonucleic acid: a self-replicating material present in nearly all living organisms

Double Helix: two chains that coil around each other form a double helix carrying the genetic instructions used in the growth, development, functioning, and reproduction of all known living organisms and many viruses.



​9. ​
Multicellular organisms have a hierarchical structural organization, in which any one          system is made up of numerous parts and is itself a component of the next level.

    In other words, we have groups of cells that make up organs, that make up bodies,
    all by working together and sharing energy.


    How do the structures of organisms enable life’s functions?
​    (choose the best answer, for a biology exam)


      a. Humans evolved thumbs only because burritos exist
      b. Cells in a body do different types of work by having shapes that help them do the
          work (hair cell vs skin cell)
      c. Veins are shaped like tunnels to transport nutrients
      d. B and C

​


​10. The phospholipid bilayer is a thin polar membrane made of two layers of lipid       
      molecules, a hydrophilic (likes water) phosphate head, and a hydrophobic (dislikes 
      water) tail consisting of two fatty acid chains, this is what the cell membrane is made 
      of.
Picture
Picture
​   It naturally allows non-polar particles (fat-soluble molecules) like oxygen (O2) and  
   carbon dioxide (CO2) to move down the concentration gradient: from high 
   concentration to low concentration.  Some proteins allow molecules in without needing 
   to use energy because they are following the concentration gradient flow (high to low).

   How does the cell membrane move particles up the concentration gradient/ from low 
​   concentration to high concentration?

      a. enzymes
      b. active transport proteins in the cell membrane use energy,
          (ATP, cell energy) to move the molecule 

      c. Mystical doorways with magical powers
      d. neurons
​
Nutrient Transport: The blood circulatory system (cardiovascular system) delivers nutrients and oxygen to all cells in the body. It consists of the heart and the blood vessels running through the entire body.
The arteries carry 
blood away from the heart; the veins carry it back to the heart.

Fats and fat soluble 
nutrients can move directly across the lipid membrane.

Water, gasses, and other very small molecules can diffuse through the pores of the 
cell.

Active Transport: Moving against a gradient. The movement of ions or molecules across a cell membrane into a region of higher concentration, assisted by enzymes and requiring energy (ATP).

ATP: 
A
denosine Triphosphate, money in the cell world, molecular unit of currency,
          organic chemical that provides energy to drive many processes in living cells


Diffusion: is a spontaneous movement of particles from an area of high concentration to an area of low concentration

Facilitated diffusion: Stuff getting through the cell membrane through a specialized door.  The passive movement of molecules along their concentration gradient, guided by the presence of another molecule – usually an integral membrane protein forming a pore or channel. May or may not 
require energy from ATP.


​11. Cells multiply through mitosis and meiosis, what is the difference?
​
    Mitosis: 
The process in cell division by which the nucleus divides, typically consisting
    of four stages, prophase, metaphase, anaphase, and telophase,
Some textbooks list five,      breaking prophase into an early phase (called prophase) and a late phase (called   
    prometaphase). N
ormally resulting in two new nuclei, each of which contains
    a complete copy of the parental chromosomes.

    Mitosis makes two cells


    Stages: prophase, prometaphase, metaphase, anaphase, and telophase. 
      
                 OK, so PPMAT...

    
In early prophase, the cell starts to break down some structures and build others up,     
    setting the stage for division of the chromosomes.

    In late prophase (sometimes also called 
prometaphase), the mitotic spindle begins to
    capture and organize the chromosomes.

    In 
metaphase, the spindle has captured all the chromosomes and lined them up at the 
​    middle of the cell, ready to divide.

    In 
anaphase, the sister chromatids separate from each other and are pulled towards 
    opposite ends of the cell.

    In 
telophase, the cell is nearly done dividing, and it starts to re-establish its normal 
    structures as cytokinesis (division of the cell contents) takes place.


    Cytokinesis, the division of the cytoplasm to form two new cells
​
Picture
Picture
https://www.khanacademy.org/science/biology/cellular-molecular-biology/mitosis/a/phases-of-mitosis 

meiosis


A type of cell division that results in four daughter cells each with half the number of chromosomes of the parent cell, as in the production of gametes and plant spores.
  • Two-step division process, Homologue pairs separate during a first round of cell division, called meiosis I.​
  • ​Sister chromatids separate during a second round, called meiosis II.
  • ​Before entering meiosis I, a cell must first go through interphase.
  •  Prophase I: As in mitosis, the chromosomes begin to condense, but in meiosis I, they also pair up. Each chromosome carefully aligns with its homologue partner so that the two match up at corresponding positions along their full length.
  • ​Homologous chromosomes are chromosome pairs (one from each parent) that are similar in length, gene position, and centromere location.
  • Homologous chromosomes trade parts, is called crossing over.
Picture

crossing over

Picture
  • Metaphase I: homologue pairs—not individual chromosomes—line up at the metaphase plate for separation.
  • Anaphase I: the homologues are pulled apart and move apart to opposite ends of the cell.
  • Telophase I: the chromosomes arrive at opposite poles of the cell.

Meiosis II:

Cells move from meiosis I to meiosis II without copying their DNA. Meiosis II is a shorter and simpler process than meiosis I, and you may find it helpful to think of meiosis II as “mitosis for haploid cells."

Haploid: half the chromosomes

Picture
Prophase II: chromosomes condense and the nuclear envelope breaks down

Metaphase II: the chromosomes line up individually along the metaphase plate. 

A
naphase II: the sister chromatids separate and are pulled towards opposite poles of the cell.

Telophase II: nuclear membranes form around each set of chromosomes, and the chromosomes decondense

Cytokinesis: splits the chromosome sets into new cells, forming the final products of meiosis: four haploid cells 
​

Picture
https://www.khanacademy.org/science/biology/cellular-molecular-biology/meiosis/a/phases-of-meiosis 


​12. What is a haploid cell?  How is it different from a diploid cell?

​    
Haploid is the term used when a cell has half the usual number of chromosomes.
    A normal eukaryotic organism is composed of diploid 
cells, one set of chromosomes
    from each parent. However, after meiosis, the number of chromosomes in gametes
    is halved.

    D
iploid cell is a cell that contains two sets of chromosomes. This is double the haploid
    chromosome number. Each pair of chromosomes in a 
diploid cell is considered to be     
​    one homologous chromosome set

​


​13. How do organisms grow and develop?
   
​     Cell division and nutrient transport, metabolism
​


​14. What is a stem cell?

     
​      a. A cell that only exists in plants

      b. A cell that can turn into many different types of cells
      c. A blood cell
      d. All of the above
​
​Cells become specialized through differentiation


​15. How can stem cell therapy change medicine in the near future?
​
    Organ transplant, regeneration of organs using stem cells

    Embryonic stem cell: Embryonic stem cells are pluripotent stem cells derived from the
    inner cell mass of a blastocyst, an early-stage pre-implantation embryo. Human
    embryos reach the blastocyst stage 4–5 days post fertilization, at which time they     
    consist of 50–150 cells.
   

    First we are a blastocyst:
​
    Fertilization
 usually takes place in a fallopian tube that links an ovary to the uterus.
    If the fertilized egg successfully travels down the fallopian tube and implants in the
    uterus, an embryo starts growing.
​
    The embryo usually reaches the uterine cavity about 5 or 6 days after fertilization.

    
Most embryonic stem cells are derived from embryos that develop from eggs that
    have been fertilized in vitro—in an in vitro fertilization clinic—and then donated for
    research purposes with informed consent of the donors.


    It is not generally considered ethical to use embryonic stem cells, you be the judge,
    we also have somatic stem cells. 

    Pluripotent: capable of giving rise to several different cell types, can give rise to
                           all of the cell types that make up the body


    Totipotent: cells can form all the cell types in a body, even placental cells.  
                         Embryonic cells within the first couple of cell divisions after fertilization
                         are the only cells that are totipotent. 
    
    Multipotent: cells can develop into more than one cell type, but are more limited
                            than pluripotent cells; adult stem cells are considered multipotent.


                            https://stemcell.ny.gov/faqs/what-difference-between

    Somatic Stem Cell: Adult stem cells have been identified in many organs and tissues,
                                       including brain, 
bone marrow, peripheral blood, blood vessels,
                                       skeletal muscle, skin, teeth, heart, gut, liver, ovarian epithelium,
                                       and testis. They are thought to reside in a specific area of
                                       each 
tissue (called a "stem cell niche").
                                     
                                       M
ultiply by cell division to replenish dying cells and
​                                       regenerate damaged tissues. 


​16. In botany, a stoma, also called a stomata, is a pore, found in the epidermis of leaves,
     stems, and other organs, that facilitates gas exchange.
     
​     They will help the plant stay cool and hydrated in the heat of summer by holding
      water in, that are the stoma doing for plants?


      a. Maintain homeostasis in the plant
      b. Absorb water
      c. Attract pollinators
      d. Removing waste
​


​17. What do DNA and RNA stand for?


      a. Donuts with apples and river news updates
      b. Do not adapt and really neat antiques 
      c. deoxyribonucleic acid and ribonucleic acid
      d. None of the above
​


​18. DNA is made of nucleotides.  What are the four different nucleotides?


      a. Thymine, Cytosine, Adenine, or Guanine
      b. Tomato, cacao, apple, guava
      c. Tyrosine, Cytonine, Alabasternine, Goosefeathernine
      d. None of these
​


​19. What is an example of an input and output of matter and the
​      transfer and transformation of energy?

      
​      a. Plants absorbing light to make sugars through photosynthesis

      b. Animals eating food and digesting it
      c. Plankton photosynthesizing and being the base of the entire food chain of the planet
      d. All of the above
​


​20. The initial source of energy for all organisms is the _____Sun___________.

​

​
​21. What do mushrooms do?

  
      a. Decompose     
​      b. Absorb petroleum
      c. Replacewood, disposable items, packing materials
      d. All of the above
​

​
​22. What is this?
Picture
      a. A trophic level pyramid and It shows the position of an organism in a food chain,
          this is how matter and energy move through an ecosystem
     
      b. A food pyramid

      c. A chart of what we need to eat more of
      d. None of the above
​


​23. Which organisms produce their own food?


      a. Autotrophs
      b. Heterotrophs
      c. Primary consumers
      d. Secondary consumers

           Auto -Self, troph-Make, one being makes without needing another (makes cells)
           Hetero- Two/other, troph- Make, need two beings to make/ grow/ live
           Primary consumer: Insect eating grass, or a fish eating algae, a vegetarian being
           Secondary Consumer: whoever eats the insect or the fish

Plants are autotrophs, they make new cells using the Sun and CO2 from the air, except those carnivorous plants, they do both... those mixotrophs
​


​24. What is the difference between aerobic and anaerobic respiration?


      a. People should be exercising 3 times a week for 30 to 60 minutes
      b. Aerobic means it needs oxygen while anaerobic does not need oxygen
      c. Some molecules like to lift weight
      d. One is in animals while the other is in plants

Aerobic respiration is the process of producing cellular energy involving oxygen. 
  • takes place in the mitochondria and requires oxygen and glucose, and produces carbon dioxide, water, and energy. 
  • Cells break down food in the mitochondria in a long, multistep process that produces roughly 36 ATP.
  • The first step in is glycolysis, the second is the citric acid cycle and the third is the electron transport system.
  • The chemical equation is
    • C6H12O6 + 6O2 → 6CO2 + 6H2O (glucose + oxygen -> carbon dioxide + water)
    • Anaerobic processes can happen in the mitochondria or in the cytoplasm of the cell.
 
Anaerobic respiration:
 no oxygen used, examples: alcohol fermentation, lactic acid fermentation and in decomposition of organic matter. 
  • The equation is: glucose + enzymes = carbon dioxide + ethanol / lactic acid
  • ​Produces energy, ATP, less energy
  • Instead of oxygen, molecules such as sulfate (SO42-), nitrate(NO3–), or sulfur (S) are used as electron acceptors.
  • An electron acceptor is a chemical entity that accepts electrons transferred to it from another compound and oxidizes it/ breaks it down.
​


​25. What happens to ecosystems when the environment changes?


      a. All living beings try their best to adapt and survive, they might move to
        another area if possible, they try a different food source and adopt orphaned babies

      b. Nothing, it all just evolves and changes really fast, it is the miracle of life
      c. Extinction 
      d. All of the above
​


​26. When we breathe out we release carbon dioxide (CO2), plants use CO2 to make
      sugars through photosynthesis and release Oxygen (O2) in the process,
      we need oxygen to live.  This is part of the carbon cycle.


      Which human activity would have the greatest impact of the carbon cycle?

      a. Deforestation 
      b. Gold mining
      c. Petroleum extraction
      d. Fracking ​​
​
Also hurting algae and plankton


​27. True or False: Scientists believe that phytoplankton contribute between

​      50 to 85 percent of the oxygen in Earth's atmosphere.
​


​28. Which of the following could increase conservation of water in New Mexico?


      a. Improve systems of agricultural irrigation
      b. Reduce the amount of land covered by grass and lawns
      c. Reduce residential water use
      d. All of the above
​


​29. How do we connect art and biology? What are some ways in which we do this
​      and what are some ways in which we could do this?

      Biology is full of art inspiration, there are free art supplies in this world as long as we   
      source them in a sustainable way.  Biology can teach us about resource sharing and
      egalitarian communities through symbiotic relationships.



​30. We have technology that can save the planet, do you think we will start using it more?
      What are some changes that you see in the near future?

       Biofuels, solar energy wood may be replaced by mycellium (mushroom) molded
       materials, stem cell research, 3d printing with bioplastics, the use of hemp to make
       textile, fuel, paper, food, cooking oil, bioplastics, biomimicry for architecture
       and product design... 



​
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